Pedplot

Test gel plotter

Half-life estimate, not bloodwork or dosing advice. Disclaimer.

t½ 1dTmax 7h100% parentestimate

The prefilled numbers are an example input to draw the curve, not a dose; Pedplot does not suggest one. To step a dose up, add another row of the same compound with a later start day.

Peaks, troughs, and half-life
Not a blood level. The chart shows the estimated milligrams of the drug still in the body, so it will not match a lab result in ng/dL. How the model works. Washout continues after the last dose. Mixed IU and mg protocols are not summed.

Testosterone gel

Peak

100.0 mg

Trough

61.6 mg

Swing

38%

~Steady state

6d

~Washout

5.5d

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Transdermal testosterone gel (AndroGel / Testogel). Modeled as a daily input with a short apparent half-life — a sketch of topical replacement, not a serum assay. There is no ester, so the line is the dose itself. Also called AndroGel, Testosterone gel, Testogel. The half-life is an estimate. Methodology.

Half-life1d
Time to peak7h
Parent hormone100%
Example input50 mg
Example frequencyevery day
Example length12 weeks
Data qualityLow

Neither the AndroGel 1.62% label nor the Testogel SmPC states a half-life for the gel; levels return to baseline 48–96 h after the last dose. The 1 d half-life and Tmax are community estimates. How the model works.

The example curve

50 mg every day for 12 weeks. With a 1d half-life, it levels off around day 6. The row runs longer than that, so the plateau is on the chart. Between doses it runs from about 61.6 to 100 mg, a swing of 38%. Each dose is a hump, and the floor stays up. After the last dose, the tail takes about 5.5 days to fall to a few percent.

Test C4 days longer (5d vs 1d).

Sources

  1. FDA label. AndroGel 1.62% FDA label, 12.3: continuous delivery for 24 h; levels return to baseline 48–72 h after the last dose; no gel half-life stated
  2. SmPC. Testogel 16.2 mg/g UK SmPC, 5.2: levels return to baseline 72–96 h after the last dose; no gel half-life stated
  3. Community estimate. Community estimate of the apparent half-life and Tmax for daily gel