Pedplot

MK-677 plotter

Half-life estimate, not bloodwork or dosing advice. Disclaimer.

t½ 1dTmax 0.2d100% parent

To step a dose up, add another row of the same compound with a later start day. The chart is remaining active amount, not serum concentration.

Peaks, troughs, and half-life
Estimated remaining active mg. Washout continues after the last dose. Mixed IU and mg protocols are not summed.

Ibutamoren

Peak

50.0 mg

Trough

28.7 mg

Swing

43%

~Steady state

5d

~Washout

5.2d

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How to read this chart

MK-677. Oral ghrelin agonist with about a 24 hour half-life, so daily doses overlap modestly.

The default row models 25.0 mg as an oral dose, daily (ed), for 8 weeks.

Also called Ibutamoren, MK 677, Mk677.

The numbers

Half-life1d
Time to peak0.2d
Parent hormone100%
Default dose25.0 mg
Default frequencyDaily (ED)
Default duration8 weeks

What the default curve does

On that default row the model counts 56 doses. Steady state is about day 5. Washout runs to about day 5.2. In the last interval the peak is 50.0 mg and the trough is 28.7 mg, a swing of 43%.

How often a dose is still there

A half-life of 1d means each dose has mostly cleared before the next daily dose, so the line is a row of spikes.

Closest comparison

HGH has a half-life of 0.1d against 1d on this page.

Where the number comes from

Published ibutamoren half-life ~24 hours. How the model works.