Pedplot

HGH plotter

Half-life estimate, not bloodwork or dosing advice. Disclaimer.

t½ 4hTmax 4h100% parent

The prefilled numbers are an example input to draw the curve, not a dose; Pedplot does not suggest one. To step a dose up, add another row of the same compound with a later start day.

Peaks, troughs, and half-life
Not a blood level. The chart shows the estimated milligrams of the drug still in the body, so it will not match a lab result in ng/dL. How the model works. Washout continues after the last dose. Mixed IU and mg protocols are not summed.

Somatropin

Peak

2.02 mg

Trough

0.040 mg

Swing

98%

~Steady state

1d

~Washout

1d

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Human growth hormone. Plasma half-life is hours, so the chart is a daily pulse — it does not build a long-ester depot. There is no ester, so the line is the dose itself. Also called Somatropin, Growth Hormone, Human Growth Hormone.

Half-life4h
Time to peak4h
Parent hormone100%
Example input2 mg
Example frequencyevery day
Example length12 weeks
Data qualityHigh

FDA somatropin labels: SC half-life 3.8 h (Humatrope), 3.0 h (Genotropin); Tmax ~4 h (Humatrope). How the model works.

The example curve

2 mg every day for 12 weeks. With a 4h half-life, it levels off around day 1. The row runs longer than that, so the plateau is on the chart. Between doses it runs from about 0.04 to 2.02 mg, a swing of 98%. Each dose is its own spike. After the last dose, the tail takes about 1 days to fall to a few percent.

MK-6770.1 days longer (6h vs 4h).

Sources

  1. FDA label. Humatrope FDA label, 12.3 Pharmacokinetics: SC half-life 3.8 h; median Tmax 4.0 h
  2. FDA label. Genotropin FDA label, 12.3 Pharmacokinetics: SC half-life 3.0 h in GHD adults