Pedplot

Saxenda plotter

Half-life estimate, not bloodwork or dosing advice. Disclaimer.

t½ 13hTmax 12h100% parent

The prefilled numbers are an example input to draw the curve, not a dose; Pedplot does not suggest one. To step a dose up, add another row of the same compound with a later start day.

Peaks, troughs, and half-life
Not a blood level. The chart shows the estimated milligrams of the drug still in the body, so it will not match a lab result in ng/dL. How the model works. Washout continues after the last dose. Mixed IU and mg protocols are not summed.

Liraglutide

Peak

2.49 mg

Trough

1.31 mg

Swing

47%

~Steady state

3d

~Washout

3.3d

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Saxenda / Victoza. Its half-life is well under a day, so each dose clears within days, a useful contrast to weekly semaglutide. There is no ester, so the line is the dose itself. Also called Victoza, Lira, Liraglutide.

Half-life13h
Time to peak12h
Parent hormone100%
Example input1.8 mg
Example frequencyevery day
Example length8 weeks
Data qualityHigh

Victoza and Saxenda labels: elimination half-life ~13 h; peak 8–12 h after the dose. How the model works.

The example curve

1.8 mg every day for 8 weeks. With a 13h half-life, it levels off around day 3. The row runs longer than that, so the plateau is on the chart. Between doses it runs from about 1.31 to 2.49 mg, a swing of 47%. Each dose is its own spike. After the last dose, the tail takes about 3.3 days to fall to a few percent.

Sources

  1. FDA label. Victoza FDA label, 12.3 Pharmacokinetics: elimination half-life approximately 13 hours; peak 8 to 12 hours post dosing
  2. FDA label. Saxenda FDA label, 12.3 Pharmacokinetics: elimination half-life approximately 13 hours; peak at 11 hours